![]() ![]() Afterward, my son insisted that I get the cut stitched and walked me to the emergency room, where the intake doctor ruled out any medical explanation for my fall and told me to take it easy for the rest of the day. I had not hit my head and had no headache or bruises, but probably cut my chin on the bike basket.ĭuring the intervening minutes, although I remember none of this, I had apparently walked the bike to my house, brought in my backpack and helmet and put a package of spinach into the refrigerator. Transient global amnesia is a sudden, temporary loss of memory for events during, after, and sometimes before the event that caused the amnesia. I do recall feeling great as I started a slow uphill ride on my block, something I do daily, and then remember nothing else until about 30 minutes later, when I left my house to retrieve my bicycle while holding a wet paper towel under my bleeding chin. I was not dizzy, there was no obstacle I might have hit, and I have no memory of almost falling. Background and Purpose The purpose of the present study was to make an attempt to ascertain the etiology of transient global amnesia (TGA), which is still disputed more than 30 years after the first description of this clinical entity. These results can be used to counsel patients about risks of recurrence and may have implications for the understanding of TGA pathophysiology.I now wonder if what I thought was a mild concussion was really TGA when on a beautiful September morning in 2017 I seem to have fallen off my bike for no apparent reason after swimming laps. This study suggests that, in this large cohort of patients with TGA, recurrent TGA was associated with earlier age at the time of first TGA episode and higher prevalence of both personal and family history of migraine compared with isolated cases. ![]() A family history of TGA was identified in 12 individuals (1.3%) with a single episode of TGA and 4 individuals (2.8%) with recurrent episodes of TGA. Acute and subacute temporal lobe abnormalities on results of magnetic resonance imaging were seen rarely and did not require intervention. There were no electroencephalographic findings associated with increased risk of TGA recurrence. 001), and a family history of migraine in 167 individuals (18.5%) with a single episode of TGA and 44 individuals (30.8%) with recurrent episodes of TGA (P =. There was a personal history of migraine in 180 individuals (20.0%) with a single episode of TGA and 52 individuals (36.4%) with recurrent episodes of TGA (P <. The prevalence of stressful events before a TGA attack makes it hard to overlook these precipitating factors, given that stress has the potential to organically effect the brain. The mean (SD) age at first episode of TGA was 65.2 (10.0) years for individuals with a single episode vs 58.8 (10.3) years for those with recurrent episodes (P <. Transient global amnesia (TGA) is a benign memory disorder with etiologies that have been debated for a long time. The number of recurrences ranged from 1 to 9, with 137 individuals (95.8%) having 3 or fewer recurrences. The 2 groups were similar in age at inclusion, sex, identifiable triggers, and duration of anterograde amnesia. A total of 901 patients (86.3%) had a single episode of TGA and 143 (13.7%) had recurrent episodes of TGA. Of 1044 included patients, 575 (55.1%) were male, and the mean (SD) age at inclusion was 75.0 (11.5) years. Natural history, vascular risk factors, and associated. Transient global amnesia and transient ischemic attack. 632 TIA, 293 control) Zorzon M, Antonutti L, Mase G, et al. Includes 4 AMA PRA Category 1 Credit (Expires on. The main outcome measure was TGA recurrence. A detailed framework for distinguishing transient global amnesia from its most common mimics. A total of 1491 cases were reviewed and 1044 met diagnostic inclusion criteria for TGA, with the remainder excluded owing to indeterminate or alternate diagnoses or limited information available in the medical record.ĭemographics, precipitating factors, migraine history, imaging and electrodiagnostic findings, and family history of TGA were collected. This retrospective cohort study involved medical record review of patients with isolated or recurrent TGA presenting to the Mayo Clinic in Rochester, Minnesota, between August 1, 1992, and February 28, 2018. To examine risk factors for the recurrence of TGA. However, recurrence rates vary considerably among studies and there are no known risk factors for TGA. Transient global amnesia (TGA) is usually considered a benign event with a low recurrence rate. ![]()
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